Bentham Science Publishers
publishes quality research and scholarly articles with a stringent peer-
reviewing process. There are around 116 online and print journals, 150 plus
open access journals and a wide range of eBooks.
One of its eBooks is Immunology
of Pregnancy 2013 by Nathalie Lédée
Here’s a short review:
Since a September, 1992, Nature article which read: “Can there be
life without LIF?”, researchers now realize that the maternal immune system is
both a foe (it can reject the conception) and a friend (immune cells and
molecules are also necessary for successful pregnancy). Leukemia Inhibitory
Factor (LIF) when absent, prevents embryo implantation in rodents. From
fecundation to parturition, immunity acts as a Janus, required but potentially
dangerous. However, the complexity and the diversity of immunity in pregnancy
deters many from entering the field. This book will try to give a complete
overview of immunity from gametes till parturition, in brief, but with complete
chapters and subsections, each written by specialists in the field.
The importance of the topic relies not only on “the riddle of the fetal allograft”, which is per se fascinating, but on its consequences, linked to the development of IVF and in general, Assisted Reproductive Technologies (ART) / Medicine. Since the discovery that there would not be (mammalian) life without LIF, it has become clear that Immune Molecules, and in general, transient post mating inflammatory reactions are required for successful implantation. Disruptions of this process can lead to implantation failure / sterility.
This E-book provides a complete compendium of gynecological immunology, spanning from fecundation to delivery. Topics also include the role of various cell types (such as T regs ad NK cells) in implantation and uterine changes as well as the genetic regulation of immunological processes. As such it will be of interest not only to fundamental and reproductive immunologists, but more importantly, clinicians in obstetrics and gynecology.
The importance of the topic relies not only on “the riddle of the fetal allograft”, which is per se fascinating, but on its consequences, linked to the development of IVF and in general, Assisted Reproductive Technologies (ART) / Medicine. Since the discovery that there would not be (mammalian) life without LIF, it has become clear that Immune Molecules, and in general, transient post mating inflammatory reactions are required for successful implantation. Disruptions of this process can lead to implantation failure / sterility.
This E-book provides a complete compendium of gynecological immunology, spanning from fecundation to delivery. Topics also include the role of various cell types (such as T regs ad NK cells) in implantation and uterine changes as well as the genetic regulation of immunological processes. As such it will be of interest not only to fundamental and reproductive immunologists, but more importantly, clinicians in obstetrics and gynecology.
For more information on the eBook, please visit: http://benthamscience.com/ebooks/9781608057337/index.htm
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